The Lone Quark?
Never! Quarks never appear on their own. The energy required to pull two quarks apart is so massive that it is enough to make two new particles. A quark and an antiquark are created, another example of pair production.
A particle called a neutral pion is made from an up quark and an antiup quark. Moving these apart creates another up quark and an antiup quark. We now have two pairs of quarks.
Trying to separate two quarks made two more quarks.