Conservation Laws
For a particle interaction to occur the following laws must be obeyed, if either is violated the reaction will never be observed (will never happen):
Charge: Must be conserved (same total value before as the total value after)
Baryon Number: Must be conserved
Lepton Number: Must be conserved
Strangeness: Conserved in EM and Strong Interaction. Doesn’t have to be conserved in Weak Interaction